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Its ability to regenerate other antioxidants, like vitamins C and E, further amplifies its protective effects against oxidative stress

Zhou F, Li C, Zhang SY

In fact, the evidence became so compelling that in August of last year, the FDA approved semaglutide (Wegovy) for the treatment of non-cirrhotic metabolic dysfunction-associated steatohepatitis (MASH) with moderate to advanced liver fibrosis, based on the phase 3 ESSENCE trial

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When introduced into cell cultures or tissue models, the compound triggers intracellular cyclic AMP (cAMP) generation and activates downstream kinase cascades

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