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But it's also completely inert in its current state

Also, once the MCL tear has completely healed, the use of anti-inflammatory medications as a trial for determining if pain relief may also be indicated

Jumping straight to 500 mcg

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Did taking melatonin improve sleep, reduce pain, or improve shoulder function after rotator cuff surgery

FDA staff's own briefing document, posted publicly ahead of the meeting as part of the docket, proposes that TB-500 (free base) and TB-500 acetate not be added to the list, citing incomplete physicochemical characterization, a lack of evidence of effectiveness for wound healing (including an in-vitro fibroblast study in which TB-500 reportedly did not induce wound healing), and insufficient nonclinical and clinical safety data