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But, the idea is still controversial, and a large, nationwide trial of older adults, slated to test the hypothesis, hasn't started yet.

Cell Calcium 56(5):340361

This leaves open the question that there may be some other primary effect that is yet to be determined, says Ard

Professional Medical Disclaimer: This article is educational and does not constitute medical advice

According to Truveta Research presented at ISPOR 2025, side effects were the leading reason patients stopped taking GLP-1 medications, accounting for 28.2% of all discontinuations

Graham Lipkin, a Consultant Nephrologist at Queen Elizabeth Hospital Birmingham, highlights this risk: "Some of the side effects of GLP-1 medicines include dehydration, which can result in acute kidney injury (AKI)