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Intracellular ROS levels were quantitatively measured using a 2,7-dichlorodihydrofluorescein diacetate (DCFH-DA) red or green fluorescent probe, as previously reported 52
Because the small GTP-binding proteins, Ras and Rho, require posttranslational modification for membrane localization and activity and are implicated in cell cycle regulation, they are likely targets for the direct antiproliferative vascular effects of statins
Vitamin B12 is a water-soluble vitamin that plays an important role in various bodily functions, including the development and functioning of the central nervous system, the formation of red blood cells, and the synthesis of DNA