Variants in GPX1 can impair antioxidant defenses, leaving blood vessels more vulnerable to oxidative stress, inflammation, hypertension, and atherosclerosis
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We also demonstrated that this slower rate of activation is directly linked to PfK13 levels at the parasite periphery, by analysis of a PfK13 knock-sideways parasite line 8
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Fronczek R, Overeem S, Lee SY, Hegeman IM, van Pelt J, van Duinen SG, Lammers GJ, Swaab DF (2007) Hypocretin (orexin) loss in Parkinsons disease