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Researchers concluded, Our main finding is that prescribed semaglutide is associated with an increased risk of NAION. Diabetic patients who took semaglutide were more than four times more likely to develop NAION than those on non-GLP-1 medications

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For large-scale production or industrial applications, the more commonly used method is to prepare Rotarutide through synthesis methods such as biosynthesis or liquid phase synthesis, which are relatively small in laboratory scale, relatively simple in operation, and suitable for preparing small quantities of products

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