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Paradoxical effects of anti-TNF- agents in inflammatory diseases

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Unresolved ferroptosis also hinders the recovery of injured lung cells

This underscores that semaglutide is best understood as a tool within a broader, longterm weightmanagement strategy, not a standalone cure

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Loss or damage to the ICCs appears to be a dominant abnormality [3, 6, 11], where altered immune function with a shift from M2 to M1 macrophage expression and impaired regulation of haem oxygenase 1 leading to increased oxidative stress may be responsible [6, 11]