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Originally developed for type-2 diabetes, drugs such as semaglutide (Ozempic, Wegovy) from Novo Nordisk and tirzepatide (Mounjaro, Zepbound) from Eli Lilly and Company have become synonymous with modern pharmacologic weight management

The GLP-1 and GIP arms slow gastric emptying and blunt appetite (that is where nausea comes from), while the glucagon arm nudges energy expenditure and hepatic fat handling

Metabolic setpoint control mechanisms in different physiological systems at rest and during exercise

If you've experienced three or more missed doses in the past month, your PlexusDx provider may recommend the Precision Peptide Genetic Test ($99 add-on after your first month of treatment) to explore whether your genetic profile predisposes you to benefit more from tirzepatide or a dual-compound approach instead

This dual action facilitates improved fatty acid uptake and reduces hepatic lipid accumulation