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GLP-1 acts on insulin secretion and satiety: it increases insulin and decreases glucagon secretion, thereby blocking the endogenous production of glucose and decreasing glycemia after a meal

To limit free metal concentrations, the synthesis of specific chelators and subsequent sequestration of metal complexes are of major importance

Luther JM, Byrne LM, Yu C, Wang TJ, Brown NJ

10.3390/molecules16086732 38 JiangH.WangX.HuangL.LuoZ.SuT.DingK.et al (2011)

Regardless of the benefits of these drugs, there have been studies that reported a link between GLP-1 receptor agonists and an increased risk of developing pancreatitis (inflammation of the pancreas), bowel obstruction, and gastroparesis (stomach paralysis)