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Overall, combination therapy with GLP-1RA plus SGLT2i was associated with better clinical outcomes of MASLD, compared to SGLT2i monotherapy

Ozempic is FDA approved for the following: Managing blood sugar in adults with Type 2 diabetes Reducing the risk of cardiovascular events like heart attack and stroke in adults with cardiovascular disease and Type 2 diabetes Reducing the risk of lowered kidney function and end-stage kidney disease in adults with chronic kidney disease and Type 2 diabetes How to get insurance to cover Ozempic for fatty liver disease Just like weight loss, fatty liver disease is considered an off-label use of Ozempic

SURPASS-4 Compared tirzepatide with people on metformin, and/or sulfonylureas and/or SGLT-2s with Insulin Glargine in people with increased cardiovascular risk