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This faster titration timeline partly explains why retatrutide achieves greater weight loss in shorter study durations
[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Liu C., Zhang Q., Zhou H., Jin L., Liu C., Yang M., Zhao X., Ding W., Xie W., Kong H
Moreover, overcoming the current paucity of pharmacokinetic data through techniques like micro-dialysis-LC/MS/MS and physiologically based pharmacokinetic (PBPK) modeling is critical for achieving reliable cross-species dose translation and enhancing preclinical predictive value
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