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While human clinical trials remain limited, the depth of animal research, consistency of positive findings across multiple study designs, and extensive community experience create a reasonable basis for therapeutic use

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Statistical significance was determined by Students t -test or using analysis of variance (ANOVA) with Tukey tests for post hoc comparisons at a 1% or 5% significance level of difference

A separate concern runs across all four Day 1 compounds: the free base versus acetate salt form distinction

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Changing it on your own can disrupt this delicate balance