doi: 10.1097/MED.0b013e3282f43a73 89 MaceOJTehanBMarshallF
The post says FDA approval for non-diabetic weight management did not arrive until 2021, but a GLP-1 receptor agonist had already received a chronic weight management approval several years before that
Retrieved February 4, 2026
Comparisons With Other Diabetes Therapies Putting GLP1s in context with other antidiabetic agents offers additional insights: Thiazolidinediones (TZDs) are associated with increased fracture risk, especially in women SGLT2 inhibitors have raised concerns in some trials, particularly canagliflozin DPP-4 inhibitors appear largely neutral regarding skeletal effects Against this backdrop, GLP1s may have a neutral or possibly safer profile, though the data are not conclusive
and (8) removing the Left Without Being Seen (LWBS) measure beginning with the CY 2028 reporting period/CY 2030 payment determination
How Its Made (No Preservatives) Sterile water is produced by distillation or reverse osmosis and then sterilized, typically by autoclaving, to eliminate microbial contamination