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A 2025 preclinical study reported modulation of senescence-related pathways consistent with improved cellular function, though translation to human aging remains uncertain [17]

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On December 18, 2023, Structure Therapeutics published the latest clinical data for GSBR-1290 on its official website.175 Currently, GSBR-1290 is undergoing a 12-week Phase 2a randomized, double-blind, placebo-controlled clinical trial to assess its effectiveness in treating patients with T2DM and obesity

Though no deaths have been reported, a substantial percentage of overdose calls have required urgent medical attention

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Semaglutide has a longer track record, is widely studied, and is often easier to access and afford