type 2 diabetes glp 1 GLP-1 receptor agonists in the treatment of e GLP-1 Receptor Agonist Shortage: Challenges

By the end of the first week, many patients report that their most bothersome symptoms have improved noticeably, though some lingering mild queasiness may persist

How will we bridge that gap

GLP-1 and its analogues are known to exert multifaceted beneficial effects on GI physiology, including enhancement of mucosal barrier integrity, modulation of intestinal motility, and regulation of immune responses within the gut mucosa

Compounded semaglutide is not going away

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Any intervention that chronically elevates GH and IGF-1 carries theoretical cancer risk concerns, since IGF-1 promotes cell proliferation and inhibits apoptosis