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This laser is the oldest pico laser on the market

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A number of clinical observations suggest that Down patients may have a functional folate deficiency despite having normal plasma levels of folate and vitamin B 12 [13]

Critical limitations identified in the systematic review include predominant use of small rodent models (primarily rats), short follow-up periods relative to human healing timelines, variable dosing regimens complicating dose-response assessment, and lack of standardized outcome measures across studies

3) summarize the potential action mechanisms of EGT against these diseases