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Higashi Y, Sasaki S, Nakagawa K, Kimura M, Noma K, Hara K, Matsuura H, Goto C, Oshima T, Chayama K, et al: Low body mass index is a risk factor for impaired endothelium-dependent vasodilation in humans: role of nitric oxide and oxidative stress

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Together with the recent studies on benzene sulphonamide derivatives 8,28 , it is clear that site I presents a druggable pocket, and our high-resolution results provide a firm basis for structure-led drug discovery

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