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Amyotrophic lateral sclerosis (ALS) is another neurodegenerative disease where oxidative stress plays a central role

Moreover, patients without preexisting conditions, such as moderate-to-severe CKD and chronic ischemic heart disease, showed more pronounced risk reductions (HR = 0.69 and HR = 0.66, respectively) than their counterparts (HR = 0.75 and HR = 0.80, respectively)

Importantly, these medications do not replace statin therapy in patients requiring lipid-lowering treatment but may provide complementary benefits in comprehensive cardiovascular risk management

Reciprocal regulation Perhaps most remarkably, estrogen and GLP-1 regulate each other

For example, diarrhoea occurs in approximately 8-17% of patients taking Ozempic and up to 20-30% with Wegovy

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