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Those exposed to the sun and pollution regularly
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It directly scavenges free radicals and also helps other antioxidants, like vitamins C and E, do their jobs
The significance of glutathione as an antioxidant and its health benefits
However, GSH itself cannot be administered clinically with any effect, and for this reason, a variety of precursors or chemically modified analogues have been generated in order to mimic glutathione's various physiological or pharmacological effects
Topical tretinoin for treating photoaging: A systematic review of randomized controlled trials
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