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Density functional theory (DFT) calculations suggested that the reaction proceeds through a step-wise mechanism, rather than a concerted, pericyclic 6e process

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Here are some of the most common side effects: Nausea Flushing (a feeling of warmth) Headache Injection site reactions Vomiting (less common) Temporary increases in blood pressure Tips to Minimize Side Effects and Monitor Reactions Taking a few simple steps can help reduce side effects and improve tolerance with PT-141

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