10.2174/1381612824666180614082950 34 KlicekR.KolencD.SuranJ.DrmicD.BrcicL.AralicaG.et al (2013)
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The ability to shuttle between the +1, +2, and +3 oxidation states is responsible for the versatile chemistry of vitamin B 12 , allowing it to serve as a donor of deoxyadenosyl radical (radical alkyl source) and as a methyl cation equivalent (electrophilic alkyl source)
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Antibody interference measurement with antihuman GIF indirect ELISA demonstrated maximal reactivity to commercial human IF, approximately onethird signal for recombinant IFs, with rat showing the greatest crossreactivity among nonhuman variants and bovine and platypus demonstrating minimal binding