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6,7,8 The antioxidant effect of uric acid can be manifested in the inhibition of cell death to protect nerves as well as profile support of NO-mediated vasodilation

Finally, while TMAOs involvement in severe COVID-19 is postulated, more research is needed to determine its significance [1822]

Oral supplementation is usually sufficient for individuals with mild to moderate deficiency due to dietary insufficiency or malabsorption disorders

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Factors such as metabolism, body composition, hydration, and dosage all influence clearance times

10.1016/0028-3908(94)90039-6 Neuropharmacology 149 MuscoliC.CuzzocreaS.NdengeleM