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Gastrointestinal side effects observed under cotadutide effects are similar in quality but more severe than those under GLP-1RA treatment (52)

Introducing Sublingual Semaglutide: A Convenient Alternative to Injections Sublingual semaglutide delivers GLP-1 medication in a format that bypasses the need for injections

Symptoms of serotonin syndrome include confusion, rapid heart rate, sweating, muscle stiffness, and, in severe cases, seizures or death (source)

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They presented some phase 2B study results entitled the ACCESS trial, and this was in adults with obesity without diabetes