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consequently, reduced or temporally/spatially mismatched Treg-derived cytokines (TGF-, IL-10, and IL-35) can weaken mucosal tolerance and reparative programs, whereas context-dependent Treg overexpansion may impair antimicrobial immunity, resulting in dysregulated intestinal homeostasis 50,51

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doi: 10.1098/rsbl.2019.0374 9 DuanYWangHMitchell-silbaughKCaiSFanFLiYet al

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