As for clinical outcomes, in the T2DM group, there was a significant reduction in HbA1c (decreased by 1.01% to 1.02%, placebo-adjusted) and a clinically meaningful decrease in body weight of 3.26% to 3.51% after 12 weeks of treatment
Its the same thing as giving someone with cancer a cancer drug, or someone with diabetes their insulin, Swisher said of the obesity drugs
The one exception where I recommend everyone avoid completely: alcohol during dose escalation weeks and heavy fried food the night before a dose increase
Protein supplementation combined with resistance training leads to greater preservation of lean mass and strength than training alone. Key point: With adequate protein intake and resistance training, patients can maintainand sometimes increasestrength during GLP-1 therapy despite overall weight loss. Recovery and micronutrients Adequate sleep, hydration, and correction of deficiencies (including vitamin D when present) further support muscle function and recovery. Bottom Line: GLP-1 Medications Improve Body Composition Not Muscle Wasting Semaglutide and tirzepatide do not inherently cause muscle wasting. Most weight lost is fat , and body composition improves. Muscle wasting is primarily a risk of undernutrition , not GLP-1 therapy itself. Protein + resistance training is the most effective strategy to preserve muscle. At Potere Health MD, GLP-1 and GIP therapy is paired with evidence-based nutrition and strength guidance so weight loss is healthier, stronger, and more sustainable
How Employers Are Managing GLP-1 Coverage Rather than eliminating coverage altogether, many employers are implementing structured management strategies designed to balance access, affordability, and outcomes
Rahmoune H, Thompson PW, Ward JM, Smith CD, Hong G, Brown J
