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Recent preclinical and clinical data suggested that LAC may exert antidepressant effects with a more rapid onset than conventional drugs. Passeri, M, et al, Acetyl-L-carnitine in the treatment of mildly demented elderly patients. in International Journal of Clincial Pharmacology Research , Volume 10, Issue 1 and 2, 1990 pp 75 - 79

The first group includes defects in the carnitine shuttle, which facilitates transport of long-chain fatty acids into the mitochondria

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This broadens the number of pathway and category relationships that may be relevant to the study framework, but it also makes it harder to isolate the contribution of one component

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