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"These results support the remarkable potential for people living with type 2 diabetes." In a 40-week Phase 3 randomized, double-blind, placebo-controlled trial for retatrutide, which included 537 participants, the drug showed average A1C reductions of up to 2% and participants lost an average of 36.6 pounds, or roughly 17% weight loss

Novo Nordisk has been particularly hard-hit, with US sales of Wegovy shrank 2% in the final three months of 2025

That was Aubrey Gordon right here on LiveWire

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however, the launch addresses a critical need as roughly 2.3 million South African adults live with diabetes, highlighting the significance of improving treatment accessibility

doi: 10.1038/nature11588 84 LupferCThomasPGAnandPKVogelPMilastaSMartinezJet al