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Gradual dose reduction over 4-8 weeks allows the body to readjust, and thyroid levels should be checked both during and after the taper, since weight stabilization changes levothyroxine requirements once again

Understanding the relationship between GLP-1 medications and skin reactions helps patients distinguish between documented adverse effects, injection site reactions, and changes related to weight loss

Current as of April 2026

When significant weight is lost quickly, the skin, which has been stretched to accommodate excess fat, may not have enough time to adjust to the new, slimmer contours of the body

Researchers also considered evidence showing that GLP-1 receptors are present in brain regions involved in reward processing

Front Microbiol [Internet]