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11 that it plans to advance its oral dual GLP-1/GIP receptor, VK-2735, into a phase III trial for obesity in the third quarter of 2026

Kanon, University College Cork, Ireland Federica Conti, Parker University, United States Updates Copyright 2026 Anlacan, Jamora, Krattinger, De Longis, Hartweg, Steinmann and Trov

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Our integrated omics analysis supports this receptor synergy by showing consistent downregulation of metabolic intermediates of fatty acid oxidation as well as pro-inflammatory and pro-fibrotic metabolites, confirming a unified pharmacodynamic effect across molecular and metabolic layers

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What does exist: specific named strains with RCT data on weight-management endpoints, which is the biology most GLP-1 users are also trying to engage