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Pyrrolidine dithiocarbamate up-regulates the expression of the genes encoding the catalytic and regulatory subunits of gamma-glutamylcysteine synthetase and increases intracellular glutathione levels

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It has been demonstrated that ferroptosis inhibitors, including deferoxamine and ferrostatin-1, can mitigate the advancement of associated diseases by preventing ferroptosis [13,14,15,16]

[DOI] [PMC free article] [PubMed] [Google Scholar] 147.Holmgren A., Lu J