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For patients with high genetic susceptibility and concomitant metabolic abnormalities, intensify dietary interventions and combination drug therapy, and dynamically monitor serum uric acid levels and inflammatory markers

In cats, 25 mcg/kg IV versus 100 mcg/kg subcutaneous, a 4-fold difference

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2a), distinct metabolic signatures were observed across the groups, indicating subtype-specific metabolic patterns

NRF2 cooperates with CBP/p300 to drive robust glutathione production, yet this interaction is dispensable for NRF2-dependent cancer cell growth