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However, while many drugs have been synthesized to target glutamine metabolism from its initial transport into the cell to its conversion to -KG, most are still in preclinical stages (Table 1) [44]

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That is a massive improvement over pramlintide, the only other amylin analog that reached commercial use

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Thereby, the reported myotendinous junction recovery [43] and restoration of full function with the stable gastric pentadecapeptide BPC 157 therapy [43] might have particular therapy potential

10.1074/jbc.M116.727479 61 KhachoM.ClarkA.SvobodaD