These in vivo results align with the in vitro data, consolidating the understanding that GHK-Cu exerts its protective effects in ALI by inhibiting excessive inflammatory responses through its anti-inflammatory and antioxidant properties, mediated by the suppression of NF-B and p38 MAPK signaling pathways [1]
[DOI] [PubMed] [Google Scholar] Pinkus R, Weiner LM, et al
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FDA materials flag compounded injectable GHK-Cu as a safety concern because of limited human safety data, aggregation risk, peptide-related impurities, and possible immunogenicity [8]
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