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Most of the studies have shown its therapeutic role in melasma, whereas some studies have contradicted this fact[] [Table 1]

We comment on some of the outstanding research questions in the field and consider the question of whether or not ergothioneine should be considered a conditionally essential micronutrient

Vision Changes: Blurred vision caused by damage to the optic nerve from prolonged deficiency

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The friction points that cause people to abandon treatment (strict fasting windows, injection anxiety, and nausea management) matter more than peak efficacy numbers recorded under controlled conditions

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