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Most improvement was achieved by BPC 157 regimens (42, 43) per-orally, parenterally and locally, even when complicated with relapse, poor healing of the fistulas, unhealed intestinal anastomosis (10, 11, 35, 42, 43) massive intestinal resection leading to short bowel (43) and functional incapability of the post-anastomotic remained intestine

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Based on existing prevention and treatment methods for PCOS, interventions targeting different nodes of the ferroptosis regulatory network combined with other treatment methods for various patient etiologies, treatments, and prognoses are expected to be effective and reasonable in the future, thus achieving personalized treatment of PCOS

Mechanistic analyses revealed that cotadutides enhanced hepatic benefits were associated with increased mitochondrial -oxidation capacity, improved mitochondrial respiratory chain function and more pronounced suppression of de novo lipogenesis enzymes

Villani et al