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However, genetic variations, impaired hepatic processing, altered enterohepatic recycling, and gut microbiota imbalances can lead to bilirubin supersaturation, increasing the risk of gallstone formation

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Beyond its classical functions in digestion and nutrient absorption, the gut microbiota is involved in regulating immune homeostasis, modulating systemic inflammation, maintaining epithelial barrier integrity, and influencing host metabolism (Adak and Khan, 2019

Glutathione is a powerful antioxidant that works to lower oxidative stress