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meningitidis population with no obvious difference between the clonal complexes mostly associated with IMD and those rarely found in IMD cases, differential gene expression has been proposed as an important determinant of the hyperinvasive phenotype (Joseph et al., 2011

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If symptoms include severe depression, hopelessness, thoughts of self-harm or an immediate risk to safety, seek urgent support

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As such, we recommend making IV vitamin therapy a weekly treatment

Physiol.-Gastrointest