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Currently, there is an ongoing randomised double-masked placebo-controlled trial, the SUMMIT trial, studying the efficacy and safety of tirzepatide, a dual agonist of glucose-dependent insulinotropic polypeptide and GLP-1 receptors, versus placebo in HFpEF patients with obesity (NCT04847557)

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Therefore, animals in a yang deficiency state may exhibit symptoms such as decreased body temperature and aversion to cold

COPD is characterized by progressive airflow limitation due to small airway remodeling and lung parenchyma destruction from emphysema, driven by chronic inflammation and oxidative stress (122)