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Similar trend was noticed regarding the presence of pesticides such as dichlorvos (0.02 mg/kg 0.03 mg/kg), omethoate (0.02 mg/kg 0.05 mg/kg), malathion (0.01 mg/kg 0.03 mg/kg), cypermethrin (0.02 mg/kg 0.03 mg/kg), and fenvalerate (0.88 mg/kg 0.70 mg/kg) in samples from plantations whereas such pesticides were not detected in those collected from supermarkets, except for dichlorvos (0.01 mg/kg 0.02 mg/kg) [90]
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In a primary culture of orbital fibroblasts from GO patients and control subjects treated with H 2 O 2 to induce OS, the antioxidants vitamin C, N-acetyl-L-cysteine, melatonin, retinol, -carotene and vitamin E were found to reduce the manifestations OS (proliferation of fibroblasts, the level of hyaluronic acid, the level of tumor necrosis factor- (TNF-), IFN- and IL1-, which provided the basis for the possible clinical use of these substances in patients with GO (87)
When it binds to copper (II) ions, it forms the GHK-Cu complex, which is the biologically active form
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