The enthusiasm for potential therapeutic use of GLP-1 derives from studies demonstrating that unlike GIP, the glucose-lowering actions of GLP-1 are preserved in patients with type 2 diabetes
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It is the first peptide that simultaneously activates three key receptors: GLP-1, GIP, and glucagon
This suggests GLP-1 activation creates durable changes in appetite regulation and food preference in the brain, not purely temporary appetite suppression
So, in 2024 on these Q-on-Q numbers, we were running somewhere between 3.9-4 percent