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The simultaneous upregulation of TIMP-1 and TIMP-2, the natural inhibitors of MMPs, suggests a regulatory influence of GHK-Cu on the balance between matrix synthesis and matrix degradation (Pickart et al., 2015)

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Key Scientific Terms+ GHK-Cu Glycyl-L-histidyl-L-lysine copper(II), a tripeptide-copper complex in human plasma that regulates collagen synthesis and stimulates hair follicle growth

The authors acknowledge with thanks WAQF and the Deanship of Scientific Research (DSR) for technical and financial support

used resveratrol as an adjuvant therapy in women with poor ovarian reserve in an attempt to prevent premature menopause (183)

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