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GLP-1 agonists were initially approved for treating type 2 diabetes, with subsequent approvals for chronic weight management and reduction of the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 diabetes

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This success story has already spawned further studies investigating the next generation of incretin drugs, including triple receptor agonists and oral peptide therapies

Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect

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Lofton, MD Winter 2015 Disclaimer: The imagery of medications used in this article does not represent actual medications