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Correspondingly, the LMNA (E358K) variant demonstrated a connection with the inhibition of ion homeostasis and cation transportation, illustrated in Fig

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Studies have demonstrated that the lifespan of mice with OC is considerably reduced owing to the continuous activity of N1ICD, which leads to the aging of endothelial cells, increased expression of chemokines and the adhesion molecule VCAM1, and facilitates recruitment of neutrophils and invasion of tumors (70,74)

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Retatrutide is contraindicated during pregnancy and breastfeeding