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[47] Burmeister, M.A., Ayala, J., Drucker, D.J., Ayala, J.E

The typical recommended dosage ranges between 500 mg and 2 grams per day, depending on fitness goals and body weight

Prolonged energy deficit and weight loss often reduce circulating insulin levels, and similar reductions in insulin have been observed for GLP1 agonist users

These symptoms are typically mild to moderate and tend to improve over time, especially with gradual dose titration as recommended

She added that distributors have even started rationing supplies, limiting bulk orders to ensure broader access