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When patients report improvement, clinicians can reinforce adherence to both metabolic and dermatologic treatment plans

Disease modifying agents capable of controlling obesity with meaningful metabolic improvement have reshaped expectations for both clinicians and patients ( Nausea and vomiting remain among the most frequent and disruptive adverse effects across Glucagon-like peptide (GLP-1)-based therapies ( In this opinion article, we examine the mechanisms underlying nausea and vomiting in semaglutide, CagriSema, survodutide, tirzepatide, retatrutide, and orforglipron and situate them within obesity clinical practice ( We also propose practical strategies to mitigate gastrointestinal intolerance

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Further clinical development is ongoing

These pharmacies have to meet high standards for sourcing raw ingredients, preparing medications in controlled environments, and testing for quality, purity, and consistency

The participant returned to the study site and completed the study