retatrutide first week 🚨Breaking: Retatrutide's Phase 3 T2D data just dropped. ▸ A1C: −2.0% at 40 weeks ▸ Weight: −36.6 lbs (−16.8%) at 12 mg ▸ No weight loss plateau — curve still descending Retatrutide study sees significant weight

Semaglutide belongs to a class of medications known as GLP-1 receptor agonists, which mimic the effects of glucagon-like peptide-1 (GLP-1), a naturally occurring hormone produced in the intestines

Try to get some patterns in place, understanding that you may need to work a little harder at those changes if you come off of the medication. Recognizing this shift can help patients to prepare, rather than mistake it for personal failure

Studies have shown (83) reported that GLP-1R is highly expressed in normal pancreatic secretory cells, expressed at low level in pancreatic acinar cells, not expressed in pancreatic duct cells, and expressed at low or no levels in human pancreatic cancer tissues

If were working on eating disorder treatment focusing primarily on just weight loss, it does kind of go against the ethos of what were working toward. Ihlenfeld added that some small studies have found GLP-1s may help reduce binge eating behaviors

In December 2024 tirzepatide was approved by the FDA for the treatment of moderate to severe obstructive sleep apnea in adults with obesity

Side effects may be more noticeable during escalation, although the pattern can differ by person