The effect of tirzepatide on 24-hour mean systolic BP, diastolic BP, and heart rate (HR) measured during 24-hour ambulatory BP monitoring (ABPM) in individuals living with obesity without T2DM, has been evaluated in the SURMOUNT-1 ABPM sub-study.34 After 36 weeks of treatment, tirzepatide was associated with statistically significant and clinically meaningful reductions in the mean 24-hour systolic BP at all doses and reduced diastolic BP at the 2 lower doses.34 Simultaneously, tirzepatide treatment was associated with a dose-dependent increase in the mean 24-hour HR.34 Fortunately, there is no clear evidence that tirzepatide increases the risk of atrial fibrillation.35 5
But his boss, then-Chief Scientific Officer Mads Krogsgaard Thomsen, had a different vision one that would ultimately reshape how the world treats obesity and diabetes
All of these together help improve the bodys blood sugar control
doi: 10.1021/acsnano.4c00392
10.2337/db08-1084 15 DaviesM.PieberT
Eating smaller, more frequent meals can stabilize blood sugar and prevent energy dips