While correlation does not equal causation, the parallel decline of a regenerative peptide and the onset of hair thinning is biologically plausible and suggests that topical GHK-Cu supplementation could compensate for what the body no longer produces in sufficient quantities
Ristoff E, Mayatepek E, Larsson A: Long-term clinical outcome in patients with glutathione synthetase deficiency
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TGR inhibitors do not react covalently with GSH, selenocysteine, or TGR, and inhibition of TGR is reversible To evaluate stability of the TGR inhibitors in the presence of GSH and selenocysteine, compound 2 and a known covalent inhibitor of TGR, TRi-1 20,45 , were incubated with GSH or the N-Boc protected methyl ester of selenocysteine, and the reaction mixtures were analyzed by LCMS (Supplementary Figs
Tissue remodeling, collagen synthesis, and vascular repair processes are well underway by this point, and the cumulative effects of consistent dosing become clearly apparent
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