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The initial attempts to induce DE differentiation using small-molecule cocktails containing CHIR and IDE1 (CI-I and CI) proved inefficient
8 Prospects for cell replacement and regenerative medicine The therapeutic application of stem cells in neurodegenerative diseases, such as ALS, has increasingly focused on their paracrine actions rather than direct neuronal replacement
Endocrine 83 (2), 259269
This process is potentially dangerous to cells, as peroxidation of mitochondrial phospholipids may affect the integrity of permeability transition pores (PTPs) and disaggregate complexes I and III of the respiratory chain, thereby enhancing electron leakage within the mitochondrial intermembrane space 5,6
Oligo dT primers and primers for real-time PCR were obtained from Integrated DNA Technologies (IDT, Coralville, IA, USA)
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