The blocking of the lysosomal iron translocation of CSCs by inhibiting the divalent metal transporter 1 (DMT1) leads to iron accumulation and cell death with features of ferroptosis (Turcu et al., 2020)
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137 , 22852296 (2012) Gao, Q., Zhang, W., Song, B., Zhang, R., Guo, W., Yuan, J.: Development of a novel lysosome-targeted ruthenium (II) complex for phosphorescence/time-gated luminescence assay of biothiols
Study of antioxidant levels in patients with multiple myeloma
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Furthermore, Gpr183 antagonism reduced CD4 + T cell adhesion to BBB spheroids exposed to CSF of MS patients (Caratis et al., 2025b)